Frontotemporal Dementia vs. Alzheimer’s Disease: Key differences in symptoms and stages |

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Frontotemporal Dementia vs. Alzheimer’s Disease: Key differences in symptoms and stages

Dementia is a condition that affects the brain, making memory, thinking, and daily life harder. Two common types are Alzheimer’s disease and frontotemporal dementia (FTD). While both cause problems with thinking and behaviour, they affect people differently. Alzheimer’s usually starts with memory problems, whereas FTD often begins with changes in personality or language. Understanding the differences is important for early diagnosis, proper care, and support for patients and families. This article explains the main differences, symptoms, stages, and what to expect in simple terms.

Comparing Alzheimer’s Disease and Frontotemporal Dementia

Alzheimer’s diseaseAlzheimer’s is the most common form of dementia. It usually starts after age 65 and mainly affects memory first. People may forget recent events, struggle with daily tasks, or get lost even in familiar places. Over time, thinking, problem-solving, and reasoning also decline.

Researchers observe DNA methylation in Alzheimer’s disease

Frontotemporal Dementia (FTD)FTD is less common but often affects younger people, usually between 40 and 60. It mainly damages the frontal and temporal lobes of the brain, which control personality, behaviour, and language. People with FTD may act differently, show unusual behaviour, or have trouble speaking before memory is affected.

Differentiating the common symptoms

A study published in the NHS shows that people with frontotemporal dementia (FTD) and Alzheimer’s disease (AD) often show different patterns of thinking and behaviour. While memory problems are usually more prominent in Alzheimer’s, FTD patients may have better memory and calculation skills but struggle earlier with behaviour and language. This difference helps doctors understand and compare the symptoms of each condition.

Symptom Alzheimer’s Disease Frontotemporal Dementia (FTD)
Memory Affected early, forgetfulness is common Usually preserved early on
Behaviour Changes occur later Early changes like impulsivity, apathy, loss of social skills
Language Trouble develops later Language problems may appear early (difficulty speaking or understanding)
Mood & Emotions Anxiety, depression can appear later Emotional blunting or loss of empathy early
Orientation Gets lost or disoriented Usually stays aware of surroundings initially

Alzheimer’s disease:

  • Memory loss, especially recent events
  • Confusion or getting lost in familiar places
  • Difficulty planning or problem-solving
  • Mood changes, anxiety, or depression
  • Trouble with speaking or understanding words (later stage)

Frontotemporal Dementia (FTD):

  • Noticeable changes in behaviour or personality (apathy, impulsivity, loss of social awareness)
  • Emotional blunting or lack of empathy
  • Language difficulties: trouble speaking, finding words, or understanding speech
  • Repetitive or compulsive behaviours
  • Memory usually stays normal in early stages

Stages of Alzheimer’s disease and frontotemporal dementia

Alzheimer’s disease1. Early Stage:Forgetting recent eventsRepeating questionsMild difficulties with planning2. Moderate Stage:Memory loss worsensTrouble recognising peopleMood changes, confusion3. Severe Stage:Difficulty speaking or understandingLoss of independenceNeeds full-time careFrontotemporal Dementia1. Early Stage:Changes in personality or behaviourLack of social awarenessSpeech or language problems (in some types)2. Middle Stage:Behaviour becomes more noticeableIncreased language difficultiesLoss of insight about own actions3. Late Stage:Memory starts to declineGreater dependence for daily activitiesPossible movement problems in some cases

Why the difference matters

  • Correct diagnosis ensures the right care and support.
  • Alzheimer’s medications may not help FTD and could worsen some symptoms.
  • Early recognition helps families plan for safety, finances, and daily routines.
  • Understanding which type of dementia it is can guide participation in research and clinical trials.

Diagnosis and support

Doctors diagnose dementia through:Medical history and observation of symptomsCognitive tests for memory, language, and thinkingBrain scans to look at affected areasSometimes genetic tests or fluid biomarkerSupport for people with dementia focuses on managing symptoms through medications and therapy, providing guidance and counselling for caregivers, and creating a safe, structured daily routine that helps maintain independence and reduces stress for both patients and their families.Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before making any changes to your health routine or treatment.





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